Iodine is one of the most widely used elements both domestically and industrially. A French physician was the person to ever use lugols iodine solution in the year 1829. He prepared it by mixing elemental iodine with potassium iodide and dissolving in water. Today, the resultant compound is widely used in domestic and industrial application. Its use has been especially appreciated in scientific research. It is also known by other terms such as Markodine, iodine potassium iodide and Strong solution.
Markodine is available as an over the counter formulations such as gels, tinctures and ointments. These formulations are mainly designed for topical use where there is a need to disinfect minor skin injuries. It is common to mix the iodine with another ingredient known as povidone so as to increase the effectiveness. Another major application is the use in disinfection of water especially in emergency situation.
Lugols has a characteristic reaction in the presence of starch which is widely available in many organic compounds. When it interacts with the polysaccharides that make up starch molecules there is a blue black colour change and this is considered a positive reaction. For this reason, the solution is used in a number of biochemical experiments. The same reaction is seen when testing for a condition known as amyloidosis in living cells.
The solution is widely used in cervical cancer screening. In this test, it is applied on the vaginal wall and on the cervix under the exposure of an instrument known as a colposcope. Since normal vaginal and cervical tissues have a high amount of glycogen, they will stain brown. Abnormal or suspicious tissues do not stain adequately and appear paler. It is the light staining areas that are used to provide biopsy specimens for histological examination.
The solution has been used in a number of selected patients suffering from Graves disease. The disease is a severe form of hyperthyroidism. Administering the solution during thyroidectomy (removal of thyroid gland), helps in reducing blood loss. This benefit is, however, not seen in patients whose thyroid hormonal levels are within the normal ranges or in those that are on medication.
In the early years of its discovery, the solution was an important treatment of gout. With scientific advancement over the years, it has fallen out of favour. The same fate has befallen it for the treatment of hyperthyroidism in which case it had been the first line drug for a long time. The main side effect associated with it was inhibition of thyroid hormone synthesis (also known as the Wolff Chaikoff effect).
Macroalgae require elemental iodine for growth and survival. The element is also important for other coral reef inhabitants. For these reasons, it is heavily used in the maintenance of marine ecosystems. Its effects are mainly due to its ability to significantly reduce the number of harmful bacteria and parasites. The other major benefits are the prevention of coral reef bleaching and polyp expansion.
When used in excess, the compound may have some unwanted effects on the body. At low dilutions, it is said to have an irritating and corrosive effect on the stomach mucosa. This may be encountered when conducting endoscopic examinations. Generally, however, it is regarded as being safe.
Markodine is available as an over the counter formulations such as gels, tinctures and ointments. These formulations are mainly designed for topical use where there is a need to disinfect minor skin injuries. It is common to mix the iodine with another ingredient known as povidone so as to increase the effectiveness. Another major application is the use in disinfection of water especially in emergency situation.
Lugols has a characteristic reaction in the presence of starch which is widely available in many organic compounds. When it interacts with the polysaccharides that make up starch molecules there is a blue black colour change and this is considered a positive reaction. For this reason, the solution is used in a number of biochemical experiments. The same reaction is seen when testing for a condition known as amyloidosis in living cells.
The solution is widely used in cervical cancer screening. In this test, it is applied on the vaginal wall and on the cervix under the exposure of an instrument known as a colposcope. Since normal vaginal and cervical tissues have a high amount of glycogen, they will stain brown. Abnormal or suspicious tissues do not stain adequately and appear paler. It is the light staining areas that are used to provide biopsy specimens for histological examination.
The solution has been used in a number of selected patients suffering from Graves disease. The disease is a severe form of hyperthyroidism. Administering the solution during thyroidectomy (removal of thyroid gland), helps in reducing blood loss. This benefit is, however, not seen in patients whose thyroid hormonal levels are within the normal ranges or in those that are on medication.
In the early years of its discovery, the solution was an important treatment of gout. With scientific advancement over the years, it has fallen out of favour. The same fate has befallen it for the treatment of hyperthyroidism in which case it had been the first line drug for a long time. The main side effect associated with it was inhibition of thyroid hormone synthesis (also known as the Wolff Chaikoff effect).
Macroalgae require elemental iodine for growth and survival. The element is also important for other coral reef inhabitants. For these reasons, it is heavily used in the maintenance of marine ecosystems. Its effects are mainly due to its ability to significantly reduce the number of harmful bacteria and parasites. The other major benefits are the prevention of coral reef bleaching and polyp expansion.
When used in excess, the compound may have some unwanted effects on the body. At low dilutions, it is said to have an irritating and corrosive effect on the stomach mucosa. This may be encountered when conducting endoscopic examinations. Generally, however, it is regarded as being safe.
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